Possible Protagonist & Antagonist
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Leaks also tease character designs:
Golden statues might represent a major villain, echoing Andrew Ryan or Comstock.

A human figure against a backdrop may hint at the protagonist design, or could be a placeholder.
ADAM-like substance could return, setting the stage for familiar gameplay twists.
While delays at Cloud Chamber push the release back, fans remain hopeful: troubled AAA projects like Doom (2016) and Resident Evil 4 eventually became hits. BioShock 4 could follow the same path.